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Muscle Combats Alzheimer’s Disease and Develops Superior Brain Function

 

Researchers are finding more and more benefits of weight training. Being a Muscle Head is turning out to be a good thing.

A lead-in factor is that obesity heightens the risk of Alzheimer’s disease, likely due to increased inflammation, insulin resistance, and higher levels of harmful fat tissue in the brain. That being the case, it’s logical to assume that higher levels of muscle may be good for brain function.

That’s what they found. 

We looked to a June 29, 2023 article in “BRAIN NEWS, EXERCISE NEWS” for the details in more every-day language.

Based on human genetics data, the researchers found that those with higher lean muscle mass had a lower risk of Alzheimer’s disease and exhibited superior cognitive performance.

“We currently have no effective treatments for this debilitating disease,” the researchers lamented in the journal BMJ Medicine.

Finding a modifiable risk factor was a giant step forward.

“Potentially relevant secreted myokines include risin, brain-derived neurotrophic factor 5, and cathepsin B." (Sounds familiar.)

"Identifying the key causal pathways might lead to the development of treatments that leverage and enhance the neuroprotective effects of lean mass,” the researchers wrote.

They, however, caution that more research is necessary before these findings can inform public health or clinical practice. (What can go wrong introducing folks to sensible resistance training?)

Still, if future studies corroborate these findings, “public health efforts to increase lean mass across the population, potentially through campaigns promoting exercise and physical activity, might reduce the population burden of Alzheimer’s disease,” the researchers wrote in a media release.

Here's the link for those who want to read the whole study:  https://studyfinds.org/lean-muscle-protects-alzheimers/

My Take

I just finished a telephone consultation with a 50-year-old attorney searching for ways to keep training, while attending to his practice and finding time for his wife and daughter.

My final message to him was that retirement can be a "death sentence." (As you'll see below, Dolly Parton is of the same mind.)

 

When the time comes to close down his law practice, he must have a replacement that interests him.

In my case that's pursuing my interest in fitness: first, while practicing law part-time, and eventually devoting full time to writing books and commentaries for our website.

I've never stopped training.

It boils down to having a reason to get up every morning, training and otherwise.

Do that and you’re likely to have many more good years ahead, physical and mental.

 

Dolly Parton, 77, expressed the same thought recently: "I would never retire," she said on Greatest Radio Hits during an interview with host Ken Bruce. "I'll just hopefully drop dead in the middle of a song on stage some day, hopefully one I've written."

 

This new study reinforces the benefits of weight training over a lifetime.

Follow in the footprints of Eugen Sandow, John Grimek, Bill Pearl, and Frank Zane. They all continued to train long after retiring from competition.

Zane, the only survivor, also oversees his website and advices clients on bodybuilding: diet, training, and posing.

 

Like Carol and I, Frank and his wife are also regular walkers, driving home the need for aerobic exercise to round out a bodybuilding regimen.

Bill Pearl added biking to his training regimen after retiring from competition.

 

         

These photos at 45 and 80 show that muscle can be developed and maintained over a lifetime.

 

Bottom line: stay occupied mentally and physically.

August 1, 2023

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